Based on decades of observations of centenarians, author Dan Buettner (Blue Zones) speculates that getting up and moving around after sitting for 20 minutes may help you live longer. A rigorous new study published in the Journal of the American Heart Association (JAHA) found that older women who sat for more than 11.7 hours per day had a 30 percent increased risk of death, regardless of whether they engaged in vigorous exercise. Data has been published showing that.
Study co-author Steve Nguyen, Ph.D., a postdoctoral fellow at the University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Sciences, said that measurements of sitting and daily activity collected from a hip device worn for up to two years investigated. 6,489 women aged 63 to 99 were followed for 7 days and for 8 years for mortality. This data was collected in a study led by Herbert and Andrea LaCroix, MPH, Distinguished Professor at the Wertheim School of Public Health, as part of a long-term national project known as the Women's Health Initiative (WHI). It started in 1991 and continues today.
Nguyen's paper is the first to apply a newly validated machine learning algorithm called CHAP to examine total sitting time and duration of sedentary seizures in relation to mortality risk. “Sedentary behavior is defined as waking behavior that involves sitting or lying down with low energy expenditure,” Professor Nguyen explains. “Previous techniques for calculating sedentary behavior have used cutpoints that identify low or no movement. The CHAP algorithm uses machine learning, a type of artificial intelligence. Developed in 2018, the technology has been developed to enhance the ability to accurately distinguish between standing and sitting.'' By fine-tuning the 'sit position', Nguyen was able to analyze total sitting time and regular sitting time. became.
Sedentary behavior poses health risks because it reduces muscle contraction, blood flow, and glucose metabolism. “When you sit, blood flow slows throughout your body, reducing glucose uptake. Your muscles contract less, which reduces the amount of oxygen they need to consume to move them, which lowers your pulse rate.” ” says the doctor. LaCroix.
Unfortunately, exercise cannot reverse these negative effects. The study showed that whether women engaged in low or high amounts of moderate-to-vigorous physical activity, their risk increased similarly if they were sedentary for long periods of time.
“Even if you go for an hour of brisk walking and spend all day sitting, you're having a negative impact on your metabolism,” LaCroix says.
Based on his research, LaCroix recommends: “If you sit for about 11 hours a day, your risk starts to increase the longer you sit in a session. For example, sitting for more than 30 minutes at a time is dangerous. Sitting for only 10 minutes at a time is dangerous. It's more risky than nothing.Most people can't wake up six times an hour, but some may wake up once an hour or every 20 minutes.You don't have to. You can go anywhere and just stand there for a little while.”
But Nguyen points out that not all sitting positions are the same. “We're starting to think beyond diseases like cardiovascular disease and into cognitive impacts, including dementia,” he says. “There are cognitively stimulating activities that can lead to sedentary behavior, such as sitting while learning a new language. Perhaps sedentary behavior in such situations is bad for people overall. I don't think so.'' Dr. Nguyen recently completed a 12-month supervised study to examine the protein signature of physical activity and how it relates to dementia. For this, he received the K99 Award from the National Institute of General Medical Sciences.
LaCroix is sympathetic to the challenge of modifying sedentary behavior, but she also understands that it is necessary, even if it is not easy. “We've created this world where it's so tempting to sit down and do something. You could be glued to the TV or scroll through Instagram for hours, but you can't sit all the time. That's not what we're supposed to be as human beings, and we can reverse all of that culturally by just sitting down and not being so attracted to everything we do.”
Co-authors of the study include John Bellettiere, Blake Anuskiewicz, and Loki Natarajan of UC San Diego, Chongzhi Di of Fred Hutchinson Cancer Center, Jordan Carlson of Children's Mercy Kansas City, and the University at Buffalo. Michael J. LaMonte of
This research was partially funded by the National Institutes of Health (grants P01 AG052352, R01 HL105065, 75N92021D00001, 75N92021D00002, 75N92021D00003, 75N92021D00004, 75N92021D00005, 5T32AG058 529-03, R01DK114945) and Tobacco-Related Disease Research Program
The authors declare no competing interests.
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