Top line:
Cancer survivors who adhere to a healthy lifestyle, including non-smoking, low alcohol intake, sufficient physical activity, healthy diet, and optimal body mass index (BMI) are at increased risk of cancer-related and all-cause mortality. may decrease.
methodology:
- Cancer survivors often face long-term health problems and decreased quality of life. Although modifiable risk factors can influence cancer survival, the specific impact of adopting a healthy lifestyle on overall cancer survival is still unclear.
- Researchers in this study examined five lifestyle factors (BMI, smoking, alcohol consumption, diet, and physical activity) in 37,095 cancer survivors from the United States, United Kingdom, and China.
- A total of 18,990 cancer survivors reported never smoking, 14,768 reported light alcohol consumption, 17,260 reported a healthy diet, and 18,141 reported adequate physical activity. and 14,739 people reported their optimal BMI.
- A healthy lifestyle score is created by summing these factors, ranging from 0 to 5, with higher scores indicating a healthier lifestyle.
- During follow-up, 4,449 cancer deaths and 8,927 all-cause deaths occurred.
remove:
- Adherence to a healthy lifestyle (healthy lifestyle factors 4-5) and unfavorable lifestyle (healthy lifestyle factors 0-1) was associated with a 43% reduction in the risk of cancer-related death. (hazard ratio) [HR]0.57) and all-cause mortality (HR, 0.52).
- Each point earned on the Healthy Lifestyle Score reduced the risk of cancer-related death and all-cause mortality by 18% (adjusted HRs of 0.82 for both).
- Healthy diet contributed most to a 31% reduction in mortality risk, followed by non-smoking (23%), light alcohol consumption (14%), optimal BMI (11%), and adequate physical activity (1 %)Met. A similar decrease was seen in all-cause mortality.
- The association between healthy lifestyle scores and mortality was consistent across subgroups based on sociodemographic and cancer-related factors.
in fact:
“Consistently, our studies have shown that people with healthy lifestyles have up to a 50% lower risk of premature death compared to those without. “We further demonstrate that modification can help improve prognosis for cancer survivors,” the authors concluded.
sauce:
The study was led by Zilong Bian from the School of Public Health and Clinical Big Data and Analysis Center, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China, and was published online on January 17, 2024. international cancer journal.
Limitations:
Exposure definitions differed between the four cohorts, and lifestyle data were collected only at baseline and did not take into account potential changes during follow-up. Detailed information about cancer was also lacking.
Disclosure:
This research was supported by the Natural Science Foundation of the National Natural Science Foundation of China, the Zhejiang Provincial Outstanding Young Researchers, the Zhejiang Provincial Traditional Chinese Medicine Science and Technology Program, the National Natural Science Foundation of China, the CRUK Career Development Fellowship, and the Swedish Government. The Heart and Lung Foundation, the Swedish Research Council, and the Swedish Health, Working Life and Welfare Research Council. The authors declared that they had no conflicts of interest.
