A new study by researchers at the University of Arizona Health Sciences identifies a link between sleep deprivation and migraine attacks and suggests that improving sleep health may reduce migraine attacks in migraine sufferers. Something was suggested.
Dr. Frank Porreca is the research director of the Pain and Addiction Comprehensive Center at Arizona Health Sciences University and a professor in the Tucson College of Medicine School of Pharmacy.
Many people who suffer from migraine suffer from sleep disorders such as insomnia, difficulty falling asleep, difficulty falling asleep, poor sleep quality, excessive daytime sleepiness, being woken up from sleep due to migraine, or being forced to sleep. I am reporting that I have it. Until now, it was unclear whether migraines cause sleep deprivation or vice versa.
“It has been recognized for quite some time that there is a relationship between sleep and migraine,” said the lead researcher. Dr. Frank Porreca, director of research at the Comprehensive Center for Pain and Addiction and professor of pharmacology at the Medical College of Arizona, Tucson. “Previous research methods have relied on patient-reported information, which is subjective. We found that it does not affect sleep, but if your sleep is disrupted, you are much more likely to have a migraine attack if you are a migraine sufferer.”
Professor Porreca leads a research team that uses preclinical mouse models to assess sleep disorders, as mouse sleep architecture closely matches human sleep architecture, including cycles of deep sleep, REM sleep, and light sleep. I was there. Sleep was assessed using electroencephalogram recording and visual observation.
Researchers found that mice were more likely to experience migraine-like pain when they were sleep-deprived, but migraine-like pain did not interfere with normal sleep.
Porreca pointed out that sleep deprivation can occur for a variety of reasons, including stress. In this study, the researchers confirmed that they were studying the effects of sleep, rather than stress, on migraine headaches by giving mice new objects to explore to keep them awake.
“Mice can't help but explore new objects. They just have to go and look,” Porreca said. “I am reminded of how often teenagers are sleep-deprived because they are on their phones. Anyone who studies sleep knows that from a sleep hygiene perspective, they should keep devices in the bedroom where they are trying to sleep. They’ll say they don’t want to.”
For people with migraines, limiting the use of electronic devices before bed and following other sleep health tips can be easy ways to reduce the likelihood of a migraine attack.
“Early morning is one of the most common times when people experience migraine attacks,” Porreca says. “Migraines are much more common in women, with a 3:1 ratio of women to men, and almost all women are of childbearing age. Many people with migraines probably have children. They When they wake up with a migraine attack, they immediately feel stressed: they don't have time to take care of themselves, they have to get the kids ready for school and get ready for work. Migraine attacks occur during the most functionally unfavorable times of the day. Improving sleep is very important and will likely reduce the frequency of migraine attacks.”
The American Migraine Foundation estimates that more than 39 million people in the United States have migraines, but that number is likely much higher due to the number of people who are undiagnosed and untreated.
A paper titled “Elucidating the relationship between sleep and the direction of migraine-like pain'' was published in Brain Communications.
Other researchers involved in the study include co-first author Dr. Robson Lillo ViginPostdoctoral Researcher, and Dr. Caroline KoprzynskiAssistant Professor. paula redman, research engineer.and Dr. Edita Navratilova, associate professor, all of the School of Medicine – Tucson School of Pharmacy. Other co-authors are Dr. Hisakatsu Ito, a former postdoctoral researcher currently at the University of Toyama, Japan. Jill Rau, MD, PhD, of Honor Health's Bob Bove Neuroscience Institute; and Dr. David Dodick of the Mayo Clinic.
This research was funded in part by the National Institutes of Health under award numbers R01NS1295 and P30DA051355.
