Manager Fabien Galthie has released six players to their clubs ahead of Wales' Six Nations clash in Cardiff.
France's head coach is hoping to finish the Six Nations on a positive note after a heavy loss to Ireland, a narrow win over Scotland and a draw with Italy.
However, they will enter the final two weeks of the championship without two key players: Jonathan Danti, who is suspended, and Mathieu Jalibert, who was injured against Italy.
There is also good news with locks Thibaut Flamand and Emmanuel Mehouu returning to full fitness and Les Bleus captain Gregory Aldrit also missing the game against Italy due to injury.
Latest information on France squad ahead of Wales Test
Ahead of the match against Warren Gatland's charges, Galthie released forwards Danny Purizo, Posolo Tuilagi and Cameron Woki, as well as backs Pierre-Louis Balassi, Emilian Gayleton and Antoine Hastoy.
According to reports, Tuilange fell ill this week and despite making the most of his opportunities with first Test starts against Ireland, Scotland and Italy, he was sent back to Perpignan to get fit. .
However, this is not the case for Woki, who was completely removed from the team due to poor performance. He came off the bench against Ireland and started the second half of France's Tests, but is hoping to impress as Galthie looks set to name an entirely new second-row duo this week. I couldn't do it.
Meanwhile, Hastoy was selected as France's third flyhalf at last year's Rugby World Cup, but Gatlier's popularity has waned and despite training with the team this week, he was forced into the matchday squad. I never joined.
This means regular full-back Tomas Ramos will start at fly-half, the position he occupied when Jalibert left the pitch in Matchday 3 against Scotland. Ramos is often used in this position for the French national team, but this will be his first time starting as No. 10 for the French national team.
According to a report by rugby llamaRamos will start alongside Nolan Le Garrec in a completely new halfback combination, as Galthie is set to make extensive changes.
Louis Biel-Bialley is expected to return to the starting 15 ahead of Matisse Lebel, who was called up late to start against Scotland, and will be joined on the wing by Damien Penault. Galthie will hand over his place in the starting lineup to Stade Français star Leo Barre.
Bordeaux's youngster Nicolas Deportaire has another possibility of making his debut, and inside center Danti's void is ready to be filled by outsider Gaël Ficou.
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Advance changes
In the pack, Francois Cross returns to the side of the scrum while Aldritt is set to return as a number eight, with Charles Ollivon rounding out the loose trio.
France's new second-row partners will reportedly be Toulouse's Thibaut Flamand and Emmanuel Mairfoux. Both players returned to the team last week after missing the opening three games due to injury. This will be Mairfoux's Test debut, having qualified for the French national team following his residency.
The final change to the starting lineup will see Julien Marchand replace Pete Mauvaca in the front row, flanked by Cyril Baille and Wini Atonio.
Racing 92 star Antoine Gibert could fill a spot on the bench with his ability to cover fly-half and scrum-half, but Maxime Luuk could agree to it instead and cover the backs at 6-2 is high. Disbanded with clubmate Moefana.
It is reported that the France national team will play against Wales.
France: 15 Leo Barre, 14 Damien Penault, 13 Gael Ficou, 12 Nicolas Deporterre, 11 Louis Biel Bialley, 10 Thomas Ramos, 9 Nolan Le Garrec, 8 Gregory Aldritt (c), 7 Charles Ollibon, 6 François Clos, 5 Emmanuel Meffou, 4 Thibault Flamand, 3 Winy Atonio, 2 Julien Marchand, 1 Cyril Bayle.
Replacement: 16 Pete Mauvaca, 17 Sebastian Taofifenua, 18 Georges-Henri Colombe, 19 Romain Taofifenua, 20 Alexandre Luma, 21 Paul Boudean, 22 Maxime Luk, 23 Yoram Moefana
read more: Wales team: 5 takeaways from 'ruthless' Warren Gatland's 'daring' selection to face France in the Six Nations
